So it makes sense that these people present generally sicker. To recap, hydrogen sulfide SIBO is a type of SIBO that can now be diagnosed with a lab breath test. Despite the usefulness of breath testing, it is important to understand that some patients with SIBO may also have too much hydrogen sulfide (H2S) in their bodies, which is not a type of overgrowth that is detectable by traditional breath tests yet. And the noise level about hydrogen sulfide right now is confusing them. Its rare that I see, for a patient whos pretty ill, that just one thing breaks open the entire case. TypicalSIBO antibiotics, such as Xifaxan, Neomycin, Berberine, Neem, and oregano, can also be effective in treating H2S symptoms. So those are my clinical symptoms Ive gathered over time and I just share them. It wont hurt to test it out and see how your body reacts to it. Number one, with regard to the flat line, lets start there. As always, make sure to talk with your doctor to determine the best protocol. Anyway, so I gathered these symptoms for many years and played around with treatments. DrMR: Okay. Written by Dr. Michael Ruscio, DC on The hyperlinked study conducted in 1939 (ya, its been a while) on sulfur content present in foods further describes the specific amount of sulfur in given food products:The Sulfur Content in Food. But they only did it for like seven days. This can help make the diagnosis, but it won't treat the cause. In addition to this benefit, Epsom salt baths are also great for reducing stress, which can further help with any symptoms you might be experiencing. In fact, although most of us consume enough sulfur through our daily diets, some disorders based on an inability of our bodies to metabolize sulfur or other types of sulfur deficiencies can still occur. So Ive seen that work. Getting more specific when someone has hydrogen sulfide issues it is usually correlated with diarrhea and sometimes rotten egg smelling gas, although Ive also seen constipation in people with h2s issues. Side effects are generally mild and can include a . Then the other thing would be, there are people who have positive hydrogen or methane, but they also have hydrogen sulfide, and were not seeing that. And we get it back in the lab. Guess what? And I was going to add that, for the benefit of the listeners, its absolutely working out. And I just monitor Instagram periodically, but I replied on this one and said, Really? They showed improvements both symptomatically and with the lab results. Meaning they cant master what they already have at their disposal. And then the last thing Ill say is, when folks are doing studies with regard to hydrogen and methane breath testing, please, please know that if youre doing it right, its all about the prep and the devices used, closed capture devices, and how the laboratory does it. What do you think might be happening? (3) Amazon and the Amazon logo are trademarks of Amazon.com, Inc, or its affiliates. Honestly, it really just depends. Its a number of straws that have to be woven together to have strength and to be able to lead to that improvement that were looking for. Its not a guarantee that almost anyones symptoms are being caused by the gut. The symptoms of H2S overgrowth can be pretty debilitating, depending on the severity of the dysbiosis. People with SIBO or dysbiosis will produce even more gas than average. Lets go through the checklist that Gary has made, to make sure before you decide its hydrogen sulfide, etc. Aerodiagnostics, again, is my go-to SIBO lab. If results show flat line (no rise after 100-120 mins): AND you have below symptoms, it may be hydrogen sulfide SIBO, Consider adding hydrogen sulfide specific treatment, Digestive complaints (diarrhea, constipation, bloating, gas, etc), Pain (abdominal/visceral, pancreas & bladder, joint pain), Sensory (photophobia, intolerance to noise, tingling in extremities, numbness), Feel toxic (hydrogen sulfide is a toxic gas that can damage nerves or mitochondria in excess), Sulfur-containing foods and supplements worsen symptoms (Epsom salts, garlic, MSM, berberine sulfate, etc. It might be yeast overgrowth. Sulfur is also part of the cellular stress response, improving ATP (energy) productionso that cells can carry on normal functions even when under stress. Epsom salt baths also help and occasional antimicrobial treatment has helped me. It might be parasites. Second, verify the test was performed correctly: did you drink the solution, lab prep, etc. So when a patient presents and they have these chronic postprandial symptoms (as that definition is), then we know to test. And combine that with there was one study using, I believe, rifaximin, in the treatment of hydrogen sulfide SIBO. Its because patients were reporting all their symptoms to me, that turn out to have a flat line. But it is tenable to say that almost any symptom could be driven by a problem in the gut. And photophobia is not something that Ive seen, but its in the research. It doesnt matter what were talking about. Im resigned to using fresh ginger at night due to its cost-effectiveness. We need to validate, is this bacteria in the small intestine where it doesnt belong, or is it not? So Gary, why dont you start us off with a little bit of the current status of the testingif you feel you are fully up to speed on the details thereand then we can launch into the rest of the conversation? This is an area where I am certainly open. A low sulfur diet enables the overworked enzymes to play catch-up. This is what we do. It is typical for people with an excess amount of hydrogen sulfide gas to have their stools turn black when they take bismuth. So their actual digestive and all of these symptoms like the neuralgia and the body pain would get worse, which is unique. So how do you get bismuth? I could sit here and name 25 agents: rifaximin, and go down the line. So we have to see how this pans out. buff.ly/3JsH0FZ. And we do have a way to interpret hydrogen sulfide currently in breath testing. Different underlying hydrogen sulfide issues (SIBO, LIBO, and sulfur-sensitivity) Different diagnostics (flat line, Trio Smart, or symptoms) Different symptoms (headaches, brain fog, sulfur gas, etc), and . And there are different treatments for hydrogen sulfide. Or what are your thoughts about just adding in some bismuthor something like thatto your approach to treating SIBO, generally speaking, based on the fact that we cant measure hydrogen sulfide right now, and you dont know youre dealing with it? That seems to be a little bit better tolerated for a lot of people. So we get a flat line hydrogen methane breath test. Theres a study that used it and it had a very successful rate of treating it. I am seeing that alot of people use Allicin from garlic to treat SIBO. It takes 30 minutes to an hour for Pepto-Bismol (bismuth subsalicylate) to start working and help relieve diarrhea, upset stomach, and nausea. Essentially, they can be considered the same thing. And guess what the number one reason is for a flat line test? And we can use technologies to augment what were currently using, as long as it works. You can see a good list of low thiol foods to stick tohere. Theyre finding it in the colon and theres more work. Youll also learn some treatments that have shown promise. (2) The Ruscio Institute is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for us to earn fees by linking to Amazon.com and affiliated sites. This is invaluable! So what you could do, as we look at this whole process, is first verify that your test was done correctly. Yes, absolutely, Dr. Siebecker, thank you. Dr. Pimentel has been doing a ton of research on mapping the microbiome of the small intestine, so now we know for the first time exactly which particular . But rather, what it oftentimes looks like is, we need to string together a few different therapies. We might not have a rise in the colon with lactulose because they were on elemental diet. It was actually starting a year ago in spring, thats when the first research studies were coming out with this new technology, and they were finding diarrhea. By reducing your intake of sulfur for an extended period of time, youll give your body the break it needs to get back on track. GS: Sure, thank you. Their patient populations are so different. Great question. So thats light and noise intolerance. But what you will notice is that this main SIBO breath test is not able to detect hydrogen sulfide gas yet. Id like to thank Aerodiagnostics, my favorite SIBO lab, for making this podcast possible. Is it really hydrogen sulfide? 2. Additionally, H2S can also result from the bacterial breakdown of matter, and can therefore be produced by humans and animals in their waste and gas. Hear how our team spotted Johns previous misdiagnosis of Hashimotos Disease and customized an effective treatment plan for his constipation and fatigue. Lets not start reading everything on the Internet that we can about hydrogen sulfide SIBO and making every treatment based upon what we eat, and all the supplements that we use totally centered around that. encourages overgrowth of H2S producing bacteria to compensate. You could have a flat line test. So if you have bacteria where it doesnt belong and you eat something, the bacteria isnt going to say, On Monday Im going to eat it and Im going to ferment that and produce gas, and thats whats going to result in symptoms.. Our team of licensed nutritionists and dietitians strive to be objective, unbiased, honest and to present both sides of the argument. So thats Alinia. Now, we can begin discussing treatment options. But as an example, just looking at the SIBO biofilm data that we collected, yes, we did show a measurable benefit that was statistically significantwhere the people who are treated with SIBO herbs plus antibiofilm agents had a greater reduction in hydrogen than did patients treated with SIBO herbsbut it didnt really seem to be clinically meaningful. It seems like nitazoxanide can work on methanogens. I cant remember. Go to wholehealthdr.com, choose the type of practitioner and/or the specialty you're looking for, and/or your city or zip code! Working hand in hand, thats what youre able to glean from the data that we provide you. They offer accounts for clinicians and direct-to-consumer testing. Hi.My friend with severe constipation tested negative for SIBO ( breath test) but I suspect hydrogen sulfide, particularly because she reacted to her Espom salts ( Her legs swelled up). One interesting diagnostic approach, aside from a flat line in regular SIBO testing, is Pepto Bismol. But really, you could just add it to whatever you were doing. But the other thing that Ive seen is body pain. Bismuth has also been shown to reduce hydrogen sulfide gas in afew studies. Sorry to hear she is having trouble with the baths. And I really want to underscore that point. But I would suspect if we had comparative data, we wouldnt see a huge amount of change, if we used nuanced hydrogen-sulfide-specific treatments compared to standard SIBO treatments. It is also used to treat diarrhea and help prevent travelers' diarrhea. Then there are some herbs that we could use. My guess is the allicin didnt work for me. So I think thats probably where everyone is getting excited. If you follow those simple guidelineseven though sometimes its hard when youre not feeling well, youre looking for anything to make you feel betterI think you have the highest probability of using the hydrogen-sulfide-SIBO-nuanced treatments to your benefit. At the same time, it has antibacterial activity that may kill off both the unfriendly bacteria and the biofilms they live in. Its not a study. These large research centers are doing extraordinarily good work. Youll have to do it in the office of the provider, which makes it significantly less convenient, because now you have to hang out for three hours at a doctors office. There are also some supplement products that have bismuth in there. DrAS: Yeah. It depends on if the prep was done right, the appropriate laboratory work was done right, the right devices. Also at the same time guarding against not getting pulled into a gutter of therapies that have no relevance to your gut, and maybe even spinning your wheels. Dr. Ruscio is your leading functional and integrative doctor specializing ingut related disorders such as SIBO, leaky gut, Celiac, IBSand inthyroid disorders such as hypothyroid and hyperthyroid. Which is, yes, we need to help weed out some of the things that we dont want there, but we also have to support the gut ecosystem, if you will, to encourage balance. Its amazing how far weve come and we have farther to go. And again, Im happy to update my opinion there as the data evolves. And were going to have to do them for quite a few years. Typically, the air that is swallowed will remain in the stomach until it gradually moves through the digestive system by peristalsis. Pepto-Bismol works as an antacid to reduce excess stomach acid and so eases discomfort. Yes, I'm ready for the next steps And Get These Exclusive Bonus Items . Your thoughts on IBS Smart blood test? I know theres a preference. Yes, it is possible to overdo exercise. Id definitely talk to her doctor about this as a reaction like that is pretty unusual. Theyre drawing folks in for that purpose and thats whos seeking them out. One of the most common causes is altered intestinal motility due to nerve damage. So thanks for that, Gary! If you need a refresher on what exactly SIBO is and how its linked to IBS see the overview here. There are so many symptoms that look like other things. Irrespective of all these details, first thing, double-check that the task was done the correct way. Learn exactly what combinations of prescription and herbal antibiotics and supplements are used to treat the 3 main types of SIBO: Hydrogen, Methane, and Hydrogen Sulfide. I would also contrast with this list of symptoms. Maybe we should start with defining hydrogen sulfide SIBO for people who havent heard of it Im sure most of our audience has. And I have some patients report to me some very good results from doctors who had prescribed them Clindamycin. DrMR: Well said. Remember, with any case of SIBO, it is extremely important to rule out other underlying causes that could be contributing to bacterial overgrowth such as decreased digestive motility, and to consult with a doctor who is knowledgeable in treating patients with IBS. Usually, with antimicrobials, you will know within a week if it is going to help or not. At least in my opinion, I dont want to paint this picture that if youre struggling with symptoms, that knowing you have hydrogen sulfide SIBO is going to be the one thing thats going to take you from highly symptomatic to totally fine. Allison, will you remind people of your website, in case people wanted to hear more from you? Thats when we start to really see the notable level of improvement, where now someone is 70, 80, 90 percent improved. There are a number of different reasons why this could occur. H2S plays an important role in our bodys ability to respond to foreign pathogens by regulating inflammation (which is good when we are trying to fight off disease), memory formation, cognition, energy, gut motility, and much more. Pepto Bismol need to NOT be used in children, and no longer then 2-3 weeks in grownups. But Allison, lets go through some of these. But by and large, were having a lot of success based on everything that weve discussed. Although it is normal to produce some amounts of this gas, an excess amount can be an indicator of a certain type of gastrointestinal issue. And why do we test? It can be compounded. It could be so many different things. Dr. Gurevich tends to use bismuth and Rifaximin or bismuth and herbs. And they have been exciting. There is a third type of SIBO (besides hydrogen and methane-based SIBO) that currently does not have a test available: hydrogen sulfide SIBO. Then: 2 months biocidin 2/day followed by 2 weeks Pepto Bismol 3/day. The movement of these gases does not cause us any pain or discomfort, and will eventually be released in small amounts. Third hour represents the large intestine generally. But what I think happens all too oftencertainly the majority of the timeis a clinician or a patient overlooks tried and true therapies. But usually its more like I asked, Do you have irritation when youre urinating? Is it colonic gas? Could be parasites. I appreciate that. The breath test only measures methane and hydrogen right now. Small intestinal bacterial overgrowth, also known as SIBO, occurs when you have an excessive amount of bacteria living in in your small intestine. I contacted Dr. De Meirleirs lab, and the lab director sent me a list of antibiotics that could be used, based on the hydrogen sulfide producing organism that you find. DrMR: Hence this functional medicine, which is taking the small cropping of treatments that are often reserved for the minority. DrMR: Hey, everyone. Or maybe not, maybe it was all from last year. Pepto Bismol is an antacid . This does come back to a philosophy of improving ones gut ecology. In small amounts, hydrogen sulfide is actually a vital molecule that is needed for living organisms to survive. And why did I think it was hydrogen sulfide? I havent tried them, so I dont know. They have found that patients who perhaps may otherwise be negative for SIBO may be positive for hydrogen sulfide. They have the mycin on the end of the name of them. Most of those are actually aminoglycosides, not all of them. This can also be used as a simple diagnostic tool to determine whether H2S is playing a role in your symptoms. Every product is science-based, validated by real-world use, and personally vetted by Dr. Ruscio, DC. It for like seven days the noise level about hydrogen sulfide currently in breath testing pepto bismol hydrogen sulfide sibo alot! 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